MEGAN5 Download Page

This is the official download site for MEGAN5. Please send feed back to Daniel Huson on any problems that you encounter.

Note that MEGAN4 licenses will not work for MEGAN5.

A license for academic use of MEGAN5 is available here.
Non-academic users please contact Daniel Huson for a commercial license or a trial license.

Program installers:

MEGAN_macos_5_7_1.dmg (64-bit, MacOS X)
MEGAN_windows_5_7_1.exe (32-bit, Windows)
MEGAN_windows-x64_5_7_1.exe (64-bit, Windows)
MEGAN_unix_5_7_1.sh (64-bit, Linux, Unix)

Release notes
Manual md5sums

Auxiliary mapping files for taxon analysis:

If the BLAST or other comparison files do not contain taxon names, but do contain GI numbers, then load one of the following mapping files to allow MEGAN to determine taxon names. The file has to be unzipped before it can be used:
http://www-ab.informatik.uni-tuebingen.de/data/software/megan5/download/gi_taxid_nucl.zip
http://www-ab.informatik.uni-tuebingen.de/data/software/megan5/download/gi_taxid_prot.zip
(These are processed versions of the files "gi_taxid_nucl.dmp.gz" and "gi_taxid_prot.dmp.gz" that are available from NCBI. The unprocessed NCBI files will not work with MEGAN. These files were downloaded from NCBI and processed on 21-November-2014.)

Auxiliary mapping files for KEGG analysis:

MEGAN uses a built-in RefSeq to KEGG mapping to determine the KO number of a given gene. If the BLAST or comparison files do not contain RefSeq identifiers, but do contain GI numbers, then load the following mapping file to allow MEGAN to determine KEGG KO groups:
http://www-ab.informatik.uni-tuebingen.de/data/software/megan5/download/gi2kegg.map.gz
The built-in RefSeq to KEGG mapping file is currently out-of-date and will not work well with the latest version of NR (due to an ongoing systematic reassignment of RefSeq identifiers) and so we currently recommend that you use this GI mapping file.

Auxiliary mapping files for SEED analysis:

MEGAN uses a built-in RefSeq to SEED mapping to determine the functional role of a given gene. If the BLAST or comparison files do not contain RefSeq identifiers, but do contain GI numbers, then load the following mapping file to allow MEGAN to determine SEED functional groups:
http://www-ab.informatik.uni-tuebingen.de/data/software/megan5/download/gi2seed.map.gz
The built-in RefSeq to SEED mapping file is currently out-of-date and will not work well with the latest version of NR (due to an ongoing systematic reassignment of RefSeq identifiers) and so we currently recommend that you use this GI mapping file.

Updates of NCBI taxonomy:

To update to the latest NCBI taxonomy, download the following file:
http://www-ab2.informatik.uni-tuebingen.de/megan/taxonomy/ncbi.zip
In the installation directory of MEGAN, unzip the file in the class/resources/files directory.