MEGAN6 Download Page

This is MEGAN6, a new major update of MEGAN. This is the official download site for the most recent version. The Community Edition of the paper is described here: Huson et al,, (2016), PLoS Computational Biology
Please post questions and bug reports to the community website.


MEGAN6 Community Edition installers:

MEGAN_Community_macos_6_8_6.dmg
MEGAN_Community_unix_6_8_6.sh
MEGAN_Community_windows-x64_6_8_6.exe
MEGAN_Community_windows_32bit_6_8_6.exe

MEGAN6 Ultimate Edition installers (require license key):

MEGAN_Ultimate_macos_6_8_6.dmg
MEGAN_Ultimate_unix_6_8_6.sh
MEGAN_Ultimate_windows-x64_6_8_6.exe
MEGAN_Ultimate_windows_32bit_6_8_6.exe

MEGAN6 Ultimate Edition is licensed by Computomics GmbH

Apply for a trial license here
New feature: The Ultimate Edition comes with the latest KEGG classification and pathway files. Computomics GmbH is a licensed reseller of KEGG.

Mapping files for current NCBI-nr protein database (not containing GI numbers):

prot_acc2tax-May2017.abin.zip Protein accession to NCBI-taxonomy mapping file. Must be unzipped before use.
nucl_acc2tax-May2017.abin.zip Nucleotide accession to NCBI-taxonomy mapping file. Must be unzipped before use.
acc2interpro-Nov2016XX.abin.zip Protein accession to InterPro mapping file. Must be unzipped before use.
acc2eggnog-Oct2016X.abin.zip Protein accession to eggNOG mapping file. Must be unzipped before use.
acc2seed-May2015XX.abin.zip Protein accession to SEED mapping file. Must be unzipped before use.
acc2kegg-Nov2016X-ue.abin.zip Protein accession to KEGG mapping file. Only for use with the Ultimate Edition of MEGAN. Must be unzipped before use.

Mapping file for working with the SILVA SSU database:

SSURef_NR99_128_tax_silva_to_NCBI_synonyms.map.gz Provide this file to MEGAN as a synonyms mapping file when importing alignments against the Silva database. No need to decompress before use.

Deprecated mapping files for NCBI-nr protein database (releases until August 2016, containing GI numbers):

prot_gi2tax-Aug2016X.bin.zip GI to NCBI-taxonomy mapping file. Must be unzipped before use.
nucl_gi2tax-Aug2016.bin.zip GI to NCBI-taxonomy mapping file. Must be unzipped before use.
gi2eggnog-June2016X.bin.zip GI to eggNOG mapping file. Must be unzipped before use.
gi2interpro-June2016X.bin.zip GI to InterPro mapping file. Must be unzipped before use.
gi2seed-May2015X.bin.zip GI to SEED mapping file. Must be unzipped before use.
gi2kegg-Aug2016X-ue.bin.zip GI to KEGG mapping file. Only for use with the Ultimate Edition of MEGAN. Must be unzipped before use.

(See MEGAN5 download page for more deprecated mapping files.)

Why do some mapping files have an X in their name? These mapping files have been extended using the NCBI-nr protein database: all accessions that occur on the same header line in nr.gz are considered equivalent and any accession that does not have a mapping to a class in the classification is assigned the majority class of all equivalent accessions.

Additional files:

Release notes
Manual
md5sums