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ReadSim

Software for simulating sequencing.

 ReadSim- A Simulator for Sanger and 454 Sequencing

 

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New sequencing technology based on pyro-sequencing (as recently introduced

by 454 Life Sciences) promises to be ideally suited for metagenomic projects that seek to determine the diversity of organisms in a given environment. To develop and calibrate software to process the arising data, a sequencing simulator is required that samples reads from a given known target sequence under an error model that reflects the performance of the sequencing technology. Additionally, to simplify the comparison of pyro-sequencing and Sanger sequencing, it is desirable that both approaches can be simulated by a single program.

 

Here we provide a sequencing simulator ReadSim that simulates the sequencing of reads both for Sanger and pyro-sequencing, optionally involving mate-pairs.

 

ReadSim is no longer maintained.

All concepts of ReadSim are integrated into our new software MetaSim. (Oct 2008)

 

Use of the program is free for academic purposes at an academic institute. For all other uses, please contact the authors.

Download

ReadSim_macos_0_12.dmg

 

ReadSim_windows_0_12.exe

 

ReadSim_unix_0_12.sh

 

Manual

To find out more about the program, take a look at the user manual

 

Authors

The program was written by Ramona Schmid and Daniel Huson

 

Internal download page.
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